Study on the biomechanical effects of magnetic nanomaterials in body injury repair within the context of music intervention

  • Hailing Wang Chifeng University, Chifeng 024000, China
Keywords: repair of body injury; magnetic nanomaterials; rhythmic music intervention; wound healing speed; biomechanical effects; inflammatory reaction
Article ID: 228

Abstract

With the progression of science and technology, the application of magnetic nanomaterials in the medical domain has drawn increasing attention. Their remarkable high surface area and biocompatibility endow them with potential in the restoration of body tissues from a biomechanical perspective. This article explores the application of magnetic nanomaterials for the repair of body injuries under the influence of rhythmic music within the framework of biomechanics. The enhanced wavelet threshold denoising algorithm is employed to refine the rhythmic music, aiming to acquire music with better biomechanical-stimulating qualities. The subjects are randomly segregated into four cohorts, namely the control group (Group A), the magnetic nanomaterial group (Group B), the music intervention group (Group C), and the music intervention + magnetic nanomaterial group (Group D). The research findings manifested that, under otherwise identical conditions, the biomechanical recovery time of Group A subjects ranged from 9 to 10 days. For Group B subjects, it was between 7 and 8 days. Group C subjects had a biomechanical recovery time of 8 to 9 days, whereas that of Group D subjects was between 4 and 5 days. The P value among Group A, Group B, and Group C exceeded 0.05. However, the P value between Group D and Groups A, B, and C was less than 0.05, signifying that magnetic nanomaterials could substantially enhance the biomechanical repair efficacy of body injuries when combined with rhythmic music intervention.

References

1. Zhang Wenjuan, Xu Jingjin, Yao Liyun, et al. Comparative study of Glucosamine hydrochloride and its derivatives on repair of injury in Zebrafish bones. Chinese Journal of Comparative Medicine. 2018; 12(28): 9–14.

2. Jing Cong, Wang Zhigang, Wang Jun, et al. Research progress on spinal cord injury related signaling pathways in spinal cord repair of injury process. China Medical Herald. 2021; 18(16): 52–55.

3. Fang Jie, Zhang Wenlong. Progress of finger repair of injury with inherent digital artery defect. Chinese Journal of Anatomy and Clinics. 2020; 25(2): 202–207.

4. Li Mengxing, Wang Peixi, Chen Xianhui, et al. The Application Status of Music Therapy in Clinical Nursing. Nursing of Integrated Traditional Chinese and Western Medicine. 2018; 4(6): 205–207.

5. Duan Deqing, Zhang Zhongwei, Mao Yuangui, Zhang Hongyan. Research progress on the application of music therapy in the management of pediatric burn pain. Chinese Journal of Burns and Wound Repair. 2023; 39(3): 280–284.

6. Chen Xiaoyong, Liu Xiaoli, Fan Haiming. Biomedical Applications of Magnetic Nanomaterials. Physics. 49(6): 381–389.

7. Kang Jingru, Yang Xin, Zhang Dejun, et al. Research progress of magnetic nanolabeling detection technology in the field of biomedical instant detection. Journal of Instrumental Analysis. 2019; 38(3): 364–371.

8. Shah S, Mudigonda S, Underhill TM, et al. Prx1+ and Hic1+ Mesenchymal Progenitors Are Present Within the Epidural Fat and Dura Mater and Participate in Dural Injury Repair. Stem Cells Translational Medicine. 2022; 11(2): 200–212. doi: 10.1093/stcltm/szab014

9. Wang Y, Chiang IL, Ohara TE, et al. Long-Term Culture Captures Injury-Repair Cycles of Colonic Stem Cells. Cell. 2019; 179(5): 1144–1159. doi: 10.1016/j.cell.2019.10.015

10. Tang Na, Xueyi Wang, Jin Zhu, et al. Labelling stem cells with a nanoprobe for evaluating the homing behavior in facial nerve injury repair. Biomaterials Science. 2022; 10(3): 808–818. doi: 10.1039/D1BM01823J

11. Sharir A, Marangoni P, Zilionis R, et al. A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage. Nature Cell Biology. 2019; 21(9): 1102–1112. doi: 10.1038/s41556-019-0378-2

12. Liu B, Xin W, Tan JR, et al. Myelin sheath structure and regeneration in peripheral nerve injury repair. Proceedings of the National Academy of Sciences. 2019; 116(44): 22347–22352. doi: 10.1073/pnas.1910292116

13. Pan D, Mackinnon SE, Wood MD. Advances in the repair of segmental nerve injuries and trends in reconstruction. Muscle & Nerve. 2020; 61(6): 726–739. doi: 10.1002/mus.26797

14. Fan Lei, Can Liu, Xiuxing Chen, et al. Directing induced pluripotent stem cell derived neural stem cell fate with a three-dimensional biomimetic hydrogel for spinal cord injury repair. ACS applied materials & interfaces. 2018; 10(21): 17742–17755.

15. Petti S, Glendor U, Andersson L. World traumatic dental injury prevalence and incidence, a meta‐analysis—One billion living people have had traumatic dental injuries. Dental Traumatology. 2018; 34(2): 71–86. doi: 10.1111/edt.12389

16. Hassanen EI, Abdelrahman RE, Aboul-Ella H, et al. Mechanistic Approach on the Pulmonary Oxido-Inflammatory Stress Induced by Cobalt Ferrite Nanoparticles in Rats. Biological Trace Element Research. 2023; 202(2): 765–777. doi: 10.1007/s12011-023-03700-5

17. Shakil MS, Bhuiya MS, Morshed MR, et al. Cobalt Ferrite Nanoparticle’s Safety in Biomedical and Agricultural Applications: A Review of Recent Progress. Current Medicinal Chemistry. 2023; 30(15): 1756–1775. doi: 10.2174/0929867329666221007113951

18. Barreto da Silva T, Dias EA, Cardoso LM da F, et al. Magnetic Nanostructures and Stem Cells for Regenerative Medicine, Application in Liver Diseases. International Journal of Molecular Sciences. 2023; 24(11): 9293. doi: 10.3390/ijms24119293

19. Abd AL-Hadi MM, Ali AJ, Marweh AK, et al. Immune Responses of Mammals to Foreign Nanomaterials, Oxidative Stress and Inflammation Assays, Toxicity of Nanomaterials to Living Cells, and Nanomedicinal Applications. Journal of Current Medical Research and Opinion. 2024; 7(06): 2716–2733.

20. Aljabali AA, Obeid MA, Bashatwah RM, et al. Nanomaterials and Their Impact on the Immune System. International Journal of Molecular Sciences. 2023; 24(3): 2008. doi: 10.3390/ijms24032008

21. Gonzalez‐Hunt CP, Sanders LH. DNA damage and repair in Parkinson’s disease: Recent advances and new opportunities. Journal of Neuroscience Research. 2020; 99(1): 180–189. doi: 10.1002/jnr.24592

22. Wang W, Wang Y, Chi J, et al. hUCMSCs carrying exenatide prevent T1DM by improving intestinal microflora composition and islet tissue damage repair. Molecular Medicine. 2022; 28(1). doi: 10.1186/s10020-022-00526-0

Published
2024-12-23
How to Cite
Wang, H. (2024). Study on the biomechanical effects of magnetic nanomaterials in body injury repair within the context of music intervention. Molecular & Cellular Biomechanics, 21(4), 228. https://doi.org/10.62617/mcb228
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Article