A planning decision support model integrating bioinformatics and occupational health data with an emphasis on biomechanics

  • Jing Li Shijiazhuang Institute of Railway Technology, Shijiazhuang 050041, Hebei, China
  • Wei Liu Hebei Chemical & Pharmaceutical College, Shijiazhuang 050026, Hebei, China
  • Feifei Chen Shijiazhuang Institute of Railway Technology, Shijiazhuang 050041, Hebei, China
Keywords: occupational health; planning decision support model; bioinformatics; dynamic bacterial foraging fine-tuned efficient adaptive boosting (DBF-EAdaBoost); biomechanics
Article ID: 528

Abstract

In today’s rapidly evolving workplace environments, the integration of bioinformatics with occupational health data presents a unique opportunity to enhance employee well-being and optimize workplace safety, especially from the perspective of biomechanics. Existing systems often fail to account for individual genetic factors and the biomechanical aspects of the work environment when assessing occupational health risks, resulting in an increase in workplace-related health problems and less effective health treatments. The primary objective of this study is to develop a planning decision support model that integrates bioinformatics and occupational health data to recognize health risks and generate tailored interventions for employees. Incorporating biomechanics, we explore the impact of physical factors such as workstation ergonomics, repetitive motion patterns, and force exertion levels in the work environment on employee health, and analyze their relationship with genetic predispositions. For example, we study how specific genetic traits may interact with biomechanical stressors to increase the likelihood of musculoskeletal disorders. Initially, study data were collected from diverse sources, including bioinformatics databases and occupational health records, ensuring a comprehensive dataset for effective model training and validation. Data cleaning and Z-score normalization were used in the data preparation stage. Feature extraction was performed using Linear Discriminate Analysis (LDA) to reduce dimensionality from preprocessed data. Data fusion was accomplished by sharing information between bioinformatics and occupational health datasets, enabling a more comprehensive decision support model. The study proposed a Dynamic Bacterial Foraging fine-tuned Efficient Adaptive Boosting (DBF-EAdaBoost) method that integrates dynamic bacterial foraging optimization with adaptive boosting techniques to significantly enhance classification performance in bioinformatics and occupational health data analysis. The proposed algorithms offer high accuracy (0.93), precision (0.987), brier score (0.100), AUC (0.92), and log loss (0.314) in forecasting potential health issues based on workplace exposures, biomechanical factors, and genetic predispositions. To enhance the practicality of the research, a more detailed explanation of the implementation process and advantages of the proposed DBF-EAdaBoost algorithm is provided. Consider including real-world case studies to demonstrate the model’s application and the actual effectiveness of health interventions in real workplace environments. For instance, we can present a case where the model was applied in a manufacturing plant to predict and prevent musculoskeletal disorders among workers by analyzing their biomechanical workloads and genetic profiles, and implementing appropriate ergonomic interventions. The planning decision support model serves as a significant tool for public health officials, policymakers, and occupational health professionals, promoting data-driven decisions that enhance health outcomes.

References

1. Kuipers, S.J., Nieboer, A.P. and Cramm, J.M., 2020. Views of patients with multi-morbidity on what is important for patient-centered care in the primary care setting. BMC Family Practice, 21, pp.1-12.https://doi.org/10.1186/s12875-020-01144-7

2. Kwame, A. and Petrucka, P.M., 2021. A literature-based study of patient-centered care and communication in nurse-patient interactions: barriers, facilitators, and the way forward. BMC Nursing, 20(1), p.158.https://doi.org/10.1186/s12912-021-00684-2

3. Keij, S.M., van Duijn-Bakker, N., Stiggelbout, A.M. and Pieterse, A.H., 2021. What makes a patient ready for shared decision making? A qualitative study. Patient Education and Counseling, 104(3), pp.571-577.https://doi.org/10.1016/j.pec.2020.08.031

4. Al-Jaroodi, J., Mohamed, N. and Abukhousa, E., 2020. Health 4.0: on the way to realizing the healthcare of the future. Ieee Access, 8, pp.211189-211210.https://doi.org/10.1109/ACCESS.2020.3038858

5. Zeadally, S. and Bello, O., 2021. Harnessing the power of Internet of Things based connectivity to improve healthcare. Internet of Things, 14, p.100074.https://doi.org/10.1016/j.iot.2019.100074

6. Sharma, N., Dev, J., Mangla, M., Wadhwa, V.M., Mohanty, S.N. and Kakkar, D., 2021. A heterogeneous ensemble forecasting model for disease prediction. New Generation Computing, pp.1-15.https://doi.org/10.1007/s00354-020-00119-7

7. Javaid, M., Haleem, A. and Singh, R.P., 2024. Health informatics to enhance the healthcare industry's culture: An extensive analysis of its features, contributions, applications and limitations. Informatics and Health.https://doi.org/10.1016/j.infoh.2024.05.001

8. Marwaha, S., Knowles, J.W. and Ashley, E.A., 2022. A guide for the diagnosis of rare and undiagnosed disease: beyond the exome. Genome medicine, 14(1), p.23.https://doi.org/10.1186/s13073-022-01026-w

9. Panayides, A.S., Amini, A., Filipovic, N.D., Sharma, A., Tsaftaris, S.A., Young, A., Foran, D., Do, N., Golemati, S., Kurc, T. and Huang, K., 2020. AI in medical imaging informatics: current challenges and future directions. IEEE journal of biomedical and health informatics, 24(7), pp.1837-1857.https://doi.org/10.1109/JBHI.2020.2991043

10. Soh, E., Tsai, J.H.C., Boutain, D.M. and Pike, K., An intersectional analysis of the health status, work conditions, and nonwork conditions of the US working‐classed across class, sex, race, and nativity identities. American Journal of Industrial Medicine.https://doi.org/10.1002/ajim.23663

11. Das, S., Khanwelkar, D.R. and Maiti, J., 2024. A semi-automated coding scheme for occupational injury data: An approach using Bayesian decision support system. Expert Systems with Applications, 237, p.121610.https://doi.org/10.1016/j.eswa.2023.121610

12. Casal-Guisande, M., Comesaña-Campos, A., Dutra, I., Cerqueiro-Pequeño, J. and Bouza-Rodríguez, J.B., 2022. Design and development of an intelligent clinical decision support system applied to the evaluation of breast cancer risk. Journal of personalized medicine, 12(2), p.169.https://doi.org/10.1109/TMSCS.2017.2710194

13. Tutun, S., Johnson, M.E., Ahmed, A., Albizri, A., Irgil, S., Yesilkaya, I., Ucar, E.N., Sengun, T. and Harfouche, A., 2023. An AI-based decision support system for predicting mental health disorders. Information Systems Frontiers, 25(3), pp.1261-1276.https://doi.org/10.1007/s10796-022-10282-5

14. Reska, D., Czajkowski, M., Jurczuk, K., Boldak, C., Kwedlo, W., Bauer, W., Koszelew, J. and Kretowski, M., 2021. Integration of solutions and services for multi-omics data analysis towards personalized medicine. biocybernetics and biomedical engineering, 41(4), pp.1646-1663.https://doi.org/10.1016/j.bbe.2021.10.005

15. Patel, V., Chesmore, A., Legner, C.M. and Pandey, S., 2022. Trends in workplace wearable technologies and connected‐worker solutions for next‐generation occupational safety, health, and productivity. Advanced Intelligent Systems, 4(1), p.2100099.https://doi.org/10.1002/aisy.202100099

16. Viet, S.M., Falman, J.C., Merrill, L.S., Faustman, E.M., Savitz, D.A., Mervish, N., Barr, D.B., Peterson, L.A., Wright, R., Balshaw, D. and O'Brien, B., 2021. Human Health Exposure Analysis Resource (HHEAR): A model for incorporating the exposome into health studies. International journal of hygiene and environmental health, 235, p.113768.https://doi.org/10.1016/j.ijheh.2021.113768

17. Saravi, B., Hassel, F., Ülkümen, S., Zink, A., Shavlokhova, V., Couillard-Despres, S., Boeker, M., Obid, P. and Lang, G.M., 2022. Artificial intelligence-driven prediction modeling and decision making in spine surgery using hybrid machine learning models. Journal of Personalized Medicine, 12(4), p.509.https://doi.org/10.3390/jpm12040509

18. Kohn, M.S., Topaloglu, U., Kirkendall, E.S., Dharod, A., Wells, B.J. and Gurcan, M., 2022. Creating learning health systems and the emerging role of biomedical informatics. Learning Health Systems, 6(1), p.e10259.https://doi.org/10.1002/lrh2.10259

19. Gallagher, D., Zhao, C., Brucker, A., Massengill, J., Kramer, P., Poon, E.G. and Goldstein, B.A., 2020. Implementation and continuous monitoring of an electronic health record embedded readmissions clinical decision support tool. Journal of personalized medicine, 10(3), p.103.https://doi.org/10.3390/jpm10030103

20. Şık, A.S., Aydınoğlu, A.U. and Son, Y.A., 2021. Assessing the readiness of Turkish health information systems for integrating genetic/genomic patient data: System architecture and available terminologies, legislative, and protection of personal data. Health Policy, 125(2), pp.203-212.https://doi.org/10.1016/j.healthpol.2020.12.004

21. Khairuddin, M.Z.F., Lu Hui, P., Hasikin, K., Abd Razak, N.A., Lai, K.W., Mohd Saudi, A.S. and Ibrahim, S.S., 2022. Occupational injury risk mitigation: machine learning approach and feature optimization for smart workplace surveillance. International journal of environmental research and public health, 19(21), p.13962.https://doi.org/10.3390/ijerph192113962

22. Zhao, Z., Lu, H., Meng, R., Si, Z., Wang, H., Wang, X., Chen, J., Zheng, Y., Wang, H., Hu, J. and Zhao, Z., 2024. Risk factor analysis and risk prediction study of obesity in steelworkers: model development based on an occupational health examination cohort dataset. Lipids in Health and Disease, 23(1), p.10. https://doi.org/10.1186/s12944-023-01994-x

23. Zheng, Z., Si, Z., Wang, X., Meng, R., Wang, H., Zhao, Z., Lu, H., Wang, H., Zheng, Y., Hu, J. and He, R., 2023. Risk prediction for the development of hyperuricemia: Model development using an occupational health examination dataset. International Journal of Environmental Research and Public Health, 20(4), p.3411. https://doi.org/10.3390/ijerph20043411

Published
2025-01-02
How to Cite
Li, J., Liu, W., & Chen, F. (2025). A planning decision support model integrating bioinformatics and occupational health data with an emphasis on biomechanics. Molecular & Cellular Biomechanics, 22(1), 528. https://doi.org/10.62617/mcb528
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Article